Biochemical markers of myocyte injury in heart failure
نویسندگان
چکیده
منابع مشابه
Biochemical markers of myocyte injury in heart failure.
This review discusses the role of biochemical markers of myocyte injury in patients with chronic congestive heart failure. Heart specific assays have been developed for the measurement of cardiac troponin T (cTnT), cardiac troponin I (cTnI), heart type fatty acid binding protein (H-FABP), and myosin light chain 1 (MLC-1). Concentrations of these biochemical markers increase in the absence of is...
متن کاملMyocyte apoptosis in heart failure.
Human heart failure is preceded by a process termed cardiac remodeling in which heart chambers progressively enlarge and contractile function deteriorates. Programmed cell death (apoptosis) of cardiac muscle cells has been identified as an essential process in the progression to heart failure. The execution of the apoptotic program entails complex interactions between and execution of multiple ...
متن کامل[Biochemical markers in heart failure: are they all the same?].
Rev Esp Cardiol. 2005;58(3):241-3 241 In recent years there has been a huge proliferation in the number of studies examining the diagnostic and prognostic value of the numerous and varied biochemical markers of chronic heart failure. These markers are the mediators or expression of the neurohumoral activation associated with this disease—a consequence of left ventricular dysfunction and its hem...
متن کاملBiochemical Markers in Heart Failure: Are They All the Same?
Rev Esp Cardiol. 2005;58(3):241-3 241 In recent years there has been a huge proliferation in the number of studies examining the diagnostic and prognostic value of the numerous and varied biochemical markers of chronic heart failure. These markers are the mediators or expression of the neurohumoral activation associated with this disease—a consequence of left ventricular dysfunction and its hem...
متن کاملA mechanistic role for cardiac myocyte apoptosis in heart failure.
Heart failure is a common, lethal condition whose pathogenesis is poorly understood. Recent studies have identified low levels of myocyte apoptosis (80-250 myocytes per 10(5) nuclei) in failing human hearts. It remains unclear, however, whether this cell death is a coincidental finding, a protective process, or a causal component in pathogenesis. Using transgenic mice that express a conditional...
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ژورنال
عنوان ژورنال: Heart
سال: 2004
ISSN: 1355-6037
DOI: 10.1136/hrt.2003.023895